Dentate gyrus network dysfunctions precede the symptomatic phase in a genetic mouse model of seizures
Neuronal circuit disturbances that lead to hyperexcitability in the cortico-hippocampal network are one of body mist the landmarks of temporal lobe epilepsy.The dentate gyrus (DG) network plays an important role in regulating the excitability of the entire hippocampus by filtering and integrating information received via the perforant path.Here, we